An oxidation product of uric acid, 2,4,5,6-pyrimidinetetrone; administration to experimental animals causes hypoglycemia due to insulin liberation, followed by hyperglycemia due to destruction of the islets of Langerhans (alloxan diabetes).
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An oxidation product of uric acid, 2,4,5,6-pyrimidinetetrone; administration to experimental animals causes hypoglycemia due to insulin liberation, followed by hyperglycemia due to destruction of the islets of Langerhans (alloxan diabetes).