achrestic anemia

a form of chronic progressive macrocytic anemia that can be fatal in which the changes in bone marrow and circulating blood closely resemble those of pernicious anemia, but in which there is only transient or no response to therapy with vitamin B12; glossitis, gastrointestinal disturbances, central nervous system disease, and pyrexia are not observed, and there is only little bleeding or hemolysis.


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